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Mescaline CactiThere are 21 products.

Mescaline cacti play a very important role in Latin American shamanic culture. Mescaline is the psycho-active compound that induces intense visual effects and a strongly altered consciousness. The peyote (Lophophora williamsii) from Mexico is a well-known mescaline cactus. Besides the peyote there are other reknowned and lesser known species of mescaline cacti, such as the San Pedro (Echinopsis pachanoi) and the Peruvian Torch (Echinopsis Peruviana). We offer an interesting selection of mescaline cacti that are suitable for cultivation at home. The cuttings can simply be placed in soil and the cactus will shoot roots and grow like nothing ever happened.

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Mescaline Cacti - Click here for more info

The Ultimate Mescaline Cactus Guide

Welcome to our ultimate guide on mescaline. Below you will find details on exactly what mescaline is, which cacti it can be found in, its effects, how it is used and how to extract it - among other things. To start with, let's have a look at the contents overview.


What Are Mescaline Cacti?

With mescaline cacti is simply meant, cactus species that produce and contain the psychedelic drug mescaline. Known by manifold ethnographic work, the mescaline cacti Peyote and San Pedro have both become famous as inebriation and ritual plants, as well as medicinal plants worldwide. If we were to propose the existence of these two types deals with the mescaline cacti, however, we'd wrongly believe in a huge mistake. For there are, besides the two known representatives, a whole series of other cactus plants containing mescaline. And partly in large quantities.

VIDEO: The Origin Of Our Mescaline Cacti




Mescaline is a psychedelic compound found in a number of cactus species. Scientifically known as 3, 4, 5 trimethoxyphenethylamine, mescaline is a naturally occurring alkaloid of the phenethylamine family. Its hallucinogenic and mind friendly effects are similar to those of LSD, psilocybin, and DMT.

Mescaline containing plants have been used by indigenous people all over Mexico and South and Central America for thousands of years. Mescaline has a high affinity for the serotonin 5HT receptors in the brain and causes excitation of neurones in the frontal lobe. Why these phenomena cause hallucinations is unknown. However, it has been traditionally used by native peoples to uplifting and positive personal and social effect.

It is known that serotonin is a "happy" compound that occurs naturally in the human brain. Most modern psychotherapeutic drugs prescribed for depression affect the serotonin system in some way. It makes sense then that the positive effects of mescaline lasts for weeks after the central hallucinogenic experience. A general feeling of ease and calm with very little internal mental chatter invariably follows. There is also a connected sense of beauty with the natural world for an extended period after. Colours remain bright, especially reds and greens, and anxiety becomes a bemusing memory.

Mescaline was the first of the psychedelics to be isolated. In 1896 Arthur Heffter extracted mescaline from peyote and tested it on himself. Investigation showed that affects can be felt at 100mg, but 350 mg is needed for a psychotropic experience.

Mescaline is ingested and absorbed in the intestinal tract, which is why it takes some time to kick in. Extractions work much faster than consuming cactus chips or teas, and are far less nauseating.

It is impossible to become addicted to mescaline. Evolution has built in an anti-addiction feature. If it is taken for more than four or five days in a row, it simply stops working. Doing bigger and bigger doses is just a big fat waste of time.

Mescaline molecula


There are a number of alkaloid-containing cacti. For our purposes here, we are going to concentrate on those that contain mescaline as the prominent active compound. In other cacti, the alkaloids are in far too tiny concentrations to be active at comfortable ingestion rates. Having to drink five litres of cactus tea or eat four kilos of cactus would certainly be a trial.

Cactus containing mescaline do so at a reasonable enough concentration for ingestion to not be so challenging. Peyote leads the way for active alkaloid concentrations at between 1 - 6% of dried weight. The 1% is more likely in general. The Trichocereus family (San Pedro and Peruvian Torch cacti) has between 0.3 - 1.3%. With either species, it is usually trial and error with dosing that determines strength on a plant to plant basis.

Zamnesia has several types of mescaline cacti for sale via our Smartshop, but we have chosen to highlight our three best sellers in the paragraphs below.


Peyote mescaline cactus

Peyote, or Lophophora Williamsii, is certainly the most well-known of the mescaline containing cacti. It has appeared in literature and movies alike and is recognised for what it is globally. Drug culture or not.

Peyote is a slow growing button type cactus. It is greenish blue sometimes greyish green. Rather than spines, it has tufts of "wool" sprouting from regularly spaced aureole. It grows wild from central Mexico to northern Texas and has been used by indigenous peoples since the pre-Colombian era. An average dried button about 2cm in diameter weighs about two grams. It would take 6 - 10 of these buttons to get the desired effects.

Peyote flowers with an often solitary, but sometimes multiples of pleasingly symmetrical pink petalled flowers. They have bright yellow and saffron anthers that contain pollen. The flowers appear between March and May and are surprisingly crisp and firm for something that appears so delicate. Propagation is by seed once they have formed inside the fruit after being pollinated. Buttons can be broken off and left to dry slightly and be potted on scar down. Left to its own devices peyote will happily, albeit slowly, spread and spread.


San Pedro Mescaline Cactus

San Pedro or Trichocereus pachinoi (Echinopsis pachinoi) has become a star in its own right with a number of strains available. Their fast growing nature has seen San Pedro cacti become very popular in the last decade.

San Pedro is a columnar type cactus that grows in clumps. It has 7 - 9 ridges along which grow aureole containing clusters of small spines. A well-buttressed column can grow to four metres and contain a substantial amount of mescaline. They propagate by seed, spreading from the base with new growth or pups, and can even sprout new plants from felled columns. Left unattended, San Pedro can spread considerably - especially when columns break and several pups spring up along its length.

During seasonal full moons, the night blooming San Pedro produces large, showy white flowers the size of dinner plates. First, large flower pods appear on their own stalk. Then, some nights later, often unexpectedly, the flowers burst open. This show lasts two nights before the flowers die back to the fruiting body.


Peruvian Torch

Peruvian Torch, or Trichocereus Peruvianis, is distinguished by its long spines that fade from base to tip in the colours of wildfire. These spines are ridiculously sharp and pierce the skin with no warning prick at all. Just straight in. Far sharper than a hypodermic. Keep out of reach of children.

Peruvian Torch grows so similarly to San Pedro that it does not need its own description. It is mainly set apart because the effects are noticeably more intense and deeper in context than San Pedro. It has a more generous girth and is grey-green in the flesh rather than dark green. It grows at a similar rate under the same conditions as other cacti in this genus.



  • Bridgesii
  • Cuzcoensis
  • Fulvinanus
  • Macrogonus
  • Taquimbalensis
  • Terschekii
  • Validus
  • Werdermannianu

Most are distinguished by individual spine arrangements and overall stature. Some are thin with very prominent ridges. Others are chubby, and the ridges are less noticeable. Some have small aureole with many tiny spines. Some have well-spaced aureole with large needles. In all cases, care must be taken as every species is very, very sharp. All, however, give their own nuanced interpretation of the mescaline fuelled psychedelic experience.


Begin of mescaline trip

Each species provides a quantitatively different experience to pure mescaline. Differing alkaloid profiles that exist in each species give nuance and character to the individual experience. The enthusiastic mescaline consumer will soon find particular plants that flick all their switches in just the right way. These friends can be propagated and enjoyed for a whole lifetime.

"The ether was wearing off. The acid was long gone. But the mescaline was running strong. Good mescaline comes on slow. The first hour is all waiting. Then about halfway through the second hour, you start cursing the creep who burned you because nothing's happening. And then - ZANG!" Fear and Loathing in Las Vegas, Hunter S Thompson.

And that's how it goes. Extractions can come on faster, but eating dehydrated chips or drinking a reduction will take some time. An hour at least, sometimes four. Mescaline is absorbed in the intestinal tract. This is why it is good to fast before a mescaline session. A clean digestive tract means the consumed material is digested faster.

In the early stages, there are physical nudges and visual teasers. Gentle waves of perceptual shifts surprise and delight. Colours and sounds intensify. Natural living things take on halos. Water and sky fill with fractally receding polygons. Intense body loads come and go in waves. From crushingly hot to light and cool, the anticipation is agonisingly beautiful.

If you have been drinking teas or reductions, you are going to be purging about now. Really go with it. You will barf right up out of your boots. It is a lavishly cleansing experience. Physically intense for sure. Throwing up in that "trying to turn yourself inside out way" can be absolutely exhausting. However once done you will be floating in a multiverse of oneness with everything. Here, colours fluoresce, and a sense of languid serenity that cannot be supplanted reigns supreme. In this temporary alternate universe, all is well and conversation is easy.

The dolls house effect is common. Where objects can appear hyper coloured and flat or two-dimensional. The visual landscape may alter. Perspectives can ebb and flow, and pulsating tracings and other pleasing effects will last for many hours. Some types of cactus may only slightly alter the open eye surroundings, but put on a bright, surreal light show behind closed eyes. The movie screen of your mind becomes awash with colours and arrangements that would make Dr. Mandelbrot proud.

Dolls house effect

Feelings intensify as the hours progress. It is in this subconscious state that mescaline imparts the teachings. Mescaline, as with other psychedelics, speaks to the subconscious mind in a fundamental universal code. Once the central hallucinogenic experience is over, a refreshed and relaxed literal mind can interpret these subconscious messages for use in the real world. On other occasions, it can be damn good fun. Mescaline and concerts or social situations go hand in hand. Light shows become alive, and the music is five dimensional. Conversations glide effortlessly, and you really do see the beauty in all people.

Is it possible to have a bad trip with mescaline? Depends on what you call bad. Set and context play their important role as with other hallucinogens. State of mind entering the process plays a big part and mescaline is a master emotional amplifier. Sometimes, if you are not in the right frame of mind, it can give you a full emotional kicking. As such, should you consider the use of mescaline, it should be done somewhere you feel comfortable and safe, with someone watching over you. Large public events are not recommended for first-time users for this reason.


Weight for weight, peyote has a more profound effect than the Trichocereus family. Peyote also has a more trippy aspect to the experience with a chronic body load. Hallucinations can be jarring and resemble LSD and thought processes will be in full flow.

San Pedro offers heightened visual perception and mental flow. The physical pressure is not as intense as Peyote or Peruvian Torch, and although very intense in nature, it is not as jarring and more welcoming. Like a warm, welcoming hug from an ethereal giant. Uplifting and soothing, calming and joyous, San Pedro feels very natural. Even at the hallucinatory peak, there is a flow with which it is easy to go.

Peruvian Torch has a body load equal to that of peyote. The effects are very intense. An invisible hand clutches you by the soul and drags you down the rabbit hole, ready or not. Not necessarily super hallucinogenic, but very, very intense. Peruvian Torch feels very ceremonial, and it demands you move. It is good to have friends around and dance, dance, and dance.

Different mescaline cacti


What you will need:

  • Cactus of your choice. 6 - 10 2cm peyote buttons per person or 30cm of columnar cactus per person.
  • A juiced lemon per person
  • Several litres of water depending on how many people are partaking.
  • Large pot or cauldron.
  • Large stirring spoon.

Step one: Take your chosen cacti and being extremely aware of spines slice the ridges away from the woody heart. Peyote requires less vigilance in the spine department.

Step two: Chop up the flesh into manageable pieces.

Step three: Using a blender or food processor whisk the cactus flesh with water and the lemon juice into a bright green and gooey cactus slurry. Pour into cauldron or large pot. Repeat until all the cactus is used.

Step four: Over the lowest flame possible stir the mix until it reduces by half. Get some tunes organised as this can take some time.

Step five: Refill the pot with water and continue to stir and reduce the concoction.

Step six: Once reduced again, but before going too thick to drink, your brew is ready for consumption.

Note: Don't scorch the mixture - it becomes unbearably foul and impossible to drink. A ceramic slow cooker can be used rather than a pot and flame. Just leave the lid off so evaporation can occur and check regularly.

Handy hint: Chilling this brew makes it more bearable to drink. Even drop a few ice cubes in there. Salt helps control the taste as well. Plain salty chips as a side really help.


What you will need:

  • Water
  • Dried and pulverised cactus of your choice.
  • Juice of one lemon per serve.
  • Saucepan or pot

Step one: Mix together all ingredients over a low flame until reduced.

Step two: Add more water and reduce slightly again

Step three: Strain and consume.

preparation mescaline cactus


This is a food-safe extraction for mescaline acetate. There will be no acids or strong alkalies to deal with. The final result can be safely ingested. Many other beneficial alkaloids are left in this recipe making the experience more complete.

What you will need:

  • 100 - 300 grams of dried and pulverised cactus of your choice
  • 25g per 100g/cactus of standard builders lime (hydrated lime)
  • 300ml per 100g/cactus of pure d-limonene. Some hardware stores stock this. It is easily available online and is not flagged in any way
  • 25ml white vinegar per 100ml of d-limonene
  • Glass jars
  • Stainless steel or glass bowls
  • Plain clear water. Pre-measured bottled water is ideal. Each ring on a 600ml bottle of water is 100ml so they have a builtin measurer for future reference.
  • Rubber gloves. D-limonene can give a rash type burn if spilt on the skin and left for over half an hour. Wash off immediaely with soap and warm water.
  • Dish for evaporating.

Step one: Mix together 25g of builders lime per 100g of dried and pulverised cactus.

Step two: Slowly stir in clean water. The ideal consistency is a fluffy stiff putty. The lime aerates the mix considerably and absorbs a substantial amount of water. In fact, this will take a surprising amount of water. You have gone too far if the green fluffy putty collapses and a layer of water is on top. You will only ever do this once, it is an easy lesson learned. The mix can still be used, but there can be excess mucosa that needs to be strained.

Step three: Cover and leave to stand for at least six hours. Overnight is fine just make sure the mix can't dry out.

Step four: Wearing rubber gloves stir in 300ml of d-limonene per 100g of dried cactus. Be sure to break up the lumps and clumps, so it is a cactus and d-limonene smoothy. Leave to stand overnight.

Step five: Wearing gloves again, strain the mix through an old t-shirt or sarong. Anything with a reasonably fine weave. Set fluid aside.

Step six: Repeat steps four and five at least three times with the same cactus pulp. This makes sure that every delicious alkaloid is removed.

Step seven: If you have a heavy layer of mucosa in the strained mix you will need to separate the two. A gravy separating jug is ideal. The d-limonene can easily be decanted away.

Step eight: In glass jars, add 25ml of white vinegar per 100ml of d-limonene and shake vigorously. Leave to stand until the vinegar separates (vinegar on the bottom, d-limonene on the top) then agitate vigorously once more. Agitate and leave to rest several times.

Step nine: Use gravy separating jug to separate the vinegar and the d-limonene. With the d-limonene, repeat step eight two more times. Put vinegar in an evaporating tray.

Step ten: Evaporate the vinegar in a low 80°C oven until a sticky dark, dark, orange layer is left. This can be scraped up with a blade and used immediately. Simply wash down with a beverage of your choice.




Peyote with pups

There are many different psychoactive cacti. Out of 70 species, currently, about 300 cactus plants are known to include the psychoactive agents. And it does not always necessarily have to be mescaline. There are a variety of other psychoactive compounds detectable in the cacti or their detection is still pending. For the most part, the substances of the plants are actually not yet researched.

For example, we know through ethnobotanical research about Epithelantha micromeris and its fruits, the Chilitos, that are consumed by Indians, together with the psychoactive mini cactus for doping purposes, because they act as stimulants. Earlier on we talked about the Doñana cactus Coryphantha macromeris. Some cacti contain caffeine, such as Harrissia adscendens, Leocereus bahiensis and Cereus jamacaru (contains mescaline as well). Other fairly well known psychoactive cacti are Ariocarpus species with their numerous phenethylamines, which are regarded as "maddening drugs," the bishops' mitres, of those their operating principles are still unknown, the Opuntia, which contain many substances etc. Echinocereus triglochidiatus shall even contain the potent psychedelics 5-MeO-DMT. Many cacti can also be used for therapeutic purposes, a good number of cactus plants are edible. Cacti are versatile ethnobotanical plants.


A cactus often mentioned in connection with Peyote and San Pedro, is the Doñana or Dona-Ana cactus Coryphantha macromeris. It is called Mulato, also belongs to the indigenous sacred plants and is used for entheogenic purposes. It does not contain mescaline, but Macromerin and other (psychoactive) phenethylamines. Macromerin induces effects similar to mescaline, only weaker.


The term Fake Peyote does not mean faked cacti are sold. Fake Peyote is an indigenous term for plants that act and/or are used alike Peyote. This must, though, not contain mescaline, but can definitely house other substances. For instance, many species of these cacti Mammillaria, Ariocarpus, Obregonia, Aztekium, Pelecyphora and Turbinicarpus, but also non-cacti plants, for example, a Tillandsia species, various ragwort species and many more.


Dealing with the botanical naming is not always easy. It is generally like that, but especially with the cacti, it is a real back and forth This is partly because there is no binding recognized system, so to speak, but each cook cooks his own soup. San Pedro and his relatives were until recently still listed under the generic name Trichocereus, but now they belong to the Echinopsis genus. Formerly they were grouped to the Cereus genus. And off you go to the confusion: The mescaline containing Pterocereen are suddenly available as Stenocereus and the also psychoactive agent housing Dolichothele genus has been completely moved to the Mammillaria genus. Further examples could be added arbitrarily.

The researchers and users will be facing a problem then. What if, for example, one has the old, long common nomenclature in mind, but the commerce is already working with the new one? What if the situation was reversed? Without brand new cacti guide or detailed knowledge of the current situation, you are often in a fix. But it gets even more complicated. Even when it comes to the diversity of a species, there is disagreement: for example, with the Lophophora (Peyote) genus. Some claim there is only the species of Lophophora Williamsii with its varieties Lutea and Williamsii, others opinion are, that in addition to that, there are, apart from the Williamsii, at least the species of Lophophora Fricii, Lophophora Diffusa and Lophophora JourDiana. However, the botany of the plant is divided the most rational - all species and varieties contain mescaline and other phenethylamines.





All mescaline cacti can be grown from seed. The corresponding seed is available in both gardening and ethnobotanical stores. Cactus seeds are placed on the potting soil and perhaps covered with some sand. This is done for mould prevention. Then moisturize well and keep in greenhouse climate, for example, with a small propagator.

The seeds germinate more or less rapidly, depending on the type and are afterwards, as stable seedlings, set and transplanted into separate pots. Now we have to be patient. Gradually the cacti will grow and develop from seedlings to plants. The cacti want to be watered regularly, but not excessively. Whenever the substrate is dry. However, this can vary from cactus to cactus. Furthermore, they need one thing: light. Therefore, they have to be kept on the window sill or, in the summer, even outdoors.

Bolivian Torch (Echinopsis Lageniformis) 20 Seeds


Kicking off with a cactus cutting is a great way to get a head start on the growing process. Find out how to grow cacti from cuttings with our easy How-To Guide.


With a clean knife, simply cut a piece of a cactus, let the surface dry out completely and then just put the cuttings in the growing medium. At the vascular bundles, it will develop the new rootlets and thrive and grow as an independent.

Some cacti form kindles which are offshoots that can easily be detached from the mother plant and further cultivated. With most cacti, the vegetative propagation is a real breeze.