No, Shisha pens are designed to be a disposable product that can be enjoyed on the go and then thrown away. On average, an E-Hookah will last for roughly 600 puffs. It is these features that allow them to be cheaper than smoking cigarettes or a real hookah.
If you are looking for a reusable pen, and want to be able to use the functionality of an e-shisha in conjunction with the occasional nicotine containing e-liquid, then it would be better to look at an e-cigarette. These are non-disposable tools designed to meet the needs of the smoker, and are thus reusable. It is possible to get nicotine free e-liquids, allowing an e-cigarette to perform the role of a shisha pen for those who desire it.