The consumption of Syrian rue (Peganum harmala) can cause dizziness, vomiting, nausea, body tremors, tinnitus, bradycardia and tachycardia.
The harmala alkaloids within Syrian rue act as MAO inhibitors, this means consuming tyramine containing foods 24 hours before and after taking Syrian rue can lead to a hypertensive crisis. Be sure to follow the MAOI-Diet.
Syrian rue also acts as a serotonin reuptake inhibitor (SSRI) and should not be taken in conjunction with any other SSRI’s or anything that reacts badly with them.
Other common side effects include: dry mouth, low blood pressure, mild headaches, lethargy, trouble sleeping, blurred vision decreased sexual ability, increased appetite and a reduced tolerance to alcohol.
It should be noted, that with certain diets and medications, Syrian rue can cause high blood pressure. It is advisable to avoid its use if you suffer from it.
Syrian rue should not be taken if you are pregnant, breast-feeding or are suffering from any pre-existing serious condition.