Medical Strains Anxiety
4 min

Best Medical Cannabis Strains For Anxiety

4 min
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Cannabis has been used against anxiety for centuries by traditional medicines. Recent studies confirmed THC and CBD as possible therapeutic anxiolytic principles. What kind of anxiety disorders can be treated with cannabis, and what are the best strains? Here is a temporary answer.

Cannabis has been used to treat various forms of anxiety for centuries by traditional medicines across the world. Recent studies confirmed THC and CBD as possible therapeutic anxiolytic principles, although some participants reported increased anxiety. The disparate scientific results and patients’ autonomous experiences are believed to be based on different individual body response.

Anxiety can seriously affect our health, since sleep deprivation decreases physical performance and alertness. Prolonged sleep disorders can also impair memory and cognitive abilities. The relationship between marijuana and anxiety is not fully understood. On one hand, cannabis is used as a natural painkiller for both the mind and body. On the other hand, some people experience paranoia and even more anxiety.

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Smoking a joint won’t solve issues, that are rooted in our brain, and it doesn’t seem realistic to cure anxiety issues permanently on cannabis alone. Anyhow, more research is needed before cannabis could become a recommended treatment against severe anxiety symptoms. In the meantime, this natural remedy involves experimenting with different strains or derivatives to understand which ones best suit any specific patient’s need. Cannabis strains with low THC and high CBD content are the new frontier against anxiety and other ailments, yet a few strains rich in THC can also help.



People often treat their anxiety with cannabis as a self-prescribed medicine. Mild anxiety can be treated experimentally with cannabis derivatives containing different proportions of THC and CBD, varying doses and cannabinoids’ ratios, according to patient’s response. Severe cases of anxiety should probably be treated with low doses of THC and higher doses of CBD. Cannabis strains containing high CBD levels appeared to be more effective in helping the patient stay relaxed, sober and focused, whether alone or in uncomfortable social situations.

People with generalized anxiety or posttraumatic stress disorder usually prefer the full body and mind relaxing effects of indica strains over sativa, with a balanced content between THC and CBD. Social anxiety is a more complicated form to be treated with cannabis, because there is a fine line between being relaxed or baked, and between being social or excessively talkative, or overly paranoid.

Cannabis can help a lot or conversely worsen the issue. That’s almost impossible to predict, as it depends on a combination of individual sensitivity, social and environmental setting, and of course cannabinoids amounts and ratios.

Obsessive-compulsive disorders fall within the category of anxiety disorders and they cause repetitive thoughts or feelings, fears, actions or sensations, that cannot be fully controlled. Some common obsessions are fear of dirt or germs, fear of making mistakes or sinning, and the need for order or symmetry.

Learning to manage an obsessive-compulsive disorder can take years of intensive therapy, depending on how severely the issue manifests itself. How different cannabis strains actually interact with these kinds of symptoms is not well understood, both by science and users. At a glance it appears that the more CBD, the better for patients.



As both science and patients’ experience proofed, THC and CBD can have opposite effects on anxiety. Both CBD and THC appear to have biphasic effects, meaning, that their action can be different, and eventually opposite, based on dosage.

CBD-rich strains are usually preferred because cannabidiol reduces or eliminates the anxiogenous effect of THC. Strangely enough, some studies suggest, that THC at low doses can have an anxiolytic effect too, while this cannabinoid begins to raise anxiety after a certain threshold is surpassed in bloodstream.

Conversely, cannabidiol can act as an energizer at low doses, starting to act at as a tranquillizer and muscle relaxant at higher doses. CBD can’t be properly described as a sedative, yet it blocks some of the psychoactive effects of THC, including the eventual anxiety sensations.

Once again with cannabis it is not easy to determine what works and what doesn’t, as everyone reacts differently. A high-THC strain is certainly not the first recommendation for anxiety, yet a little of the typical THC-rich sativas euphoria might calm the effects of anxiety in many patients.



Just like any other herbal remedy, the various cannabis compounds complex is able to determine a whole “entourage effect”, that enhances the therapeutic value of a natural phytocomplex compared to any extracted or synthesized single active principle. The whole phytotherapic cannabis compound is very variable in its content of active principles, and it’s not just about THC and CBD.

Other components in cannabis resin may contribute to increase or lower anxiety. Besides the two main cannabinoids, cannabis contains a wide variety of aromatic terpenes, together with dozens of different cannabinoids.

Most of terpenes are present in trace amounts and little is known about their overall medicinal value, yet science gave evidence, that some of these terpenes have relaxing and stress relief properties, such as myrcene, or an antidepressive action like limonene.

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Reducing the amount of THC inhaled or ingested appears crucial to avoid anxiety issues. Most of cannabis strains today are THC-rich hybrids between indica and sativa, but the dominance of one or the other heritage can determine differences in the medicinal application. Indica strains exert more tranquilizing effects than sativa, helping slowing down the mind, easing nervous sensations, and bringing the body to a relaxed condition.

Sativa strains can be energizing and overstimulating, while indica are more sedative. Even so, today we have to remind, that industrial sativa hemp extracts, such as CBD oil with a high cannabidiol concentration and no THC content, do represent a safe and effective option for treating some of the anxiety symptoms in adults as much as kids, elderly, or pets.


Growing cannabis at home allows users to save big amounts of money and keep their cannabis quality always at the top. Below is a selection of strains, that can be easily cultivated with just a little patience and a small money investment. These are all strains, that might help anxiety, even if they contain a good amount of THC, except one of them, which is a new generation hybrid with higher CBD and virtually zero THC. Having a high CBD strain handy can help people with anxiety. 

1. Cannatonic - Resin Seeds

Cannatonic Resin Seeds

Cannatonic is a CBD-rich strain, that could be recommended for generalized anxiety. This cross between MK Ultra and G13 Haze has a THC:CBD ratio of almost 1:1, which exerts a well balanced action between a relaxation effect and a mild psychoactivity. This strain yields about 500g/m² or up to 400g per plant outdoors. Her flowering time is around 7 to 8 weeks.

2. Girl Scout Cookies - FastBuds

Girl Scout Cookies FastBuds

Girl Scout Cookies by FastBuds is a potent and flavourful indica-dominant strain. The effect is both stimulating and relaxing, as it promotes joy and sociality, enhances perceptions and sense of humour. These traits make it suitable for conditions like posttraumatic stress disorders. Girl Scout Cookies grows up to 60-100cm, with an autoflowering life cycle of 8-9 weeks. The yield goes up to 500-650g/m² or 70-300g per plant. The amount of THC can reach 22%, making it a medicine for experienced users. A similar smiley effect helping with social anxiety is given by Dutch Passion's Strawberry Cough. This is an easy to grow strain, that limits its THC content to a respectable, yet not excessive 12%, with a fruity taste.

3. Northern Lights - Sensi Seeds

Northern Lights Sensi Seeds

Northern Lights is one of the fundamental cannabis strains of this century. Sensi Seeds’ variety of this genetic grows easily with a flowering period of just 45-50 days. This earthy and powerful indica is able to relax, triggering a peaceful mindset and eventually distracting from some of the daytime nightmares shown in obsessive-compulsive disorders. On the same therapeutic front is Blackberry Kush. Just like most of Kush strains, this heavy indica inherits strong sedating effects from its Afghani breed. These are the perfect strains for experimenting against nighttime anxiety and insomnia.

4. CBD Therapy - CBD Crew

CBD Therapy CBD Crew

Finally, CBD Therapy by CBD Crew is a cannabis strain with a THC:CBD ratio of 1:20(+). This hybrid develops 8-10% CBD and just 0,5% THC, verified by independent laboratories. The effect induced by CBD Therapy is strictly medical, with no psychoactive action, thus it could be safely experimented to treat any kind of anxiety related disorders.


Written by: Zamnesia
Zamnesia has spent years honing its products, ranges, and knowledge of all things psychedelic. Driven by the spirit of Zammi, Zamnesia strives to bring you accurate, factual, and informative content.

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We are not making medical claims. This article has been written for informational purposes only, and is based on research published by other externals sources.

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