Cannabis And Hot Pepper
3 min

The Surprising Benefits Of Combining Cannabis And Hot Pepper

3 min
Facts News

Combining hot peppers and cannabis appears to have curative powers, extending the healing capabilities of both substances. Experiment at home with your own delicious edible pepper cannabis concoctions!

Cannabis has diverse healing properties in its own right; however, it has become clear that cannabis in combination with other natural remedies encourages even greater therapeutic outcomes.
This is frequently referred to as “The Entourage Effect.”

True for natural substances in traditional medicine, mixing cannabinoids with certain substances can bolster its curative effectiveness. Such is the case with cannabis and citrus fruits. While this practice is fairly well-documented, there is another food that makes cannabis super-effective: the spicy red pepper.

While this may seem like a bizarre combination, it can actually help to treat an upset stomach, as well as more serious medical conditions. These include illnesses stemming from inflammation of the gut or bowel region such as irritable bowel syndrome. Furthermore, cannabis and the spicy red pepper have been linked to improving symptoms of diabetes and colitis.



Most of our immune cells are actually found in our stomachs. Human diets are full of bacteria, some of which are highly beneficial. This is why an immune problem occurring in the stomach is a serious issue. In some cases, the gut becomes inflamed, after which it begins attacking its own cells. This can then lead to severe conditions like Crohn’s disease, celiac and even cancer.

Cannabis has been increasingly cited for its potential in reducing inflammation. This has led to more acceptance of cannabis in treating certain inflammatory conditions. These include diseases of the gut.


Research has established that a rise in bodily temperature stimulates the immune system. For example, a fever is a tell-tale sign that the body is fighting infection.

Now, researchers have taken this theory one step further. Immunologist and researcher at the University of Connecticut School of Medicine Pramod Srivastava has studied this issue in-depth. Publishing his findings in the Proceedings of the National Academy of Sciences, he discovered that cannabis acts as a regulator of immune homeostasis in the gut.

Srivastava also found evidence of something else. Not only does heat stimulate the immune system, apparently so does capsaicin. Capsaicin is the chemical in red peppers that makes them hot.

Immune cells exposed to capsaicin in petri dishes responded the same way they do when exposed to physical heat. Srivastava discovered that cells bind to anandamide, a “natural endocannabinoid” and capsaicin on the same receptors.

Mice fed both capsaicin or anandamide appeared to react the same way. They both experienced periods of healing and lessened inflammation of the stomach. There is also evidence that when used together, they boost each other’s effectiveness.

For now, Srivastava is continuing to break ground. He currently aspires to partner with a public health authority in Colorado. His goal? To see if there is a link between edible cannabinoid ingestion and reduction of colitis.

So there you have it! The answer to an upset stomach is not a mild food. Instead, try a canna-infused, peppery-zinger hot sauce. Word to the wise, this is not for everyone. Some people with issues of the gut report increases in gastric upset. With any further questions, consult your doctor before moving forward.

If cannabis and red pepper doesn’t work for you, never fear! A pot muffin will target the same receptors in the stomach. The world of culinary medicine beckons.

Experiment. Have fun.


Red Pepper Pasta

This delicious treat tastes divine, packing a potent dose of beneficial cannabinoids into every bite of this canna-pepper combo. This recipe is super easy to make, only requiring one pot!

Prep time depends on how you want to add cannabis to this recipe. One of the easiest methods is to prepare a canna-broth beforehand. Combine your veggies (celery, onions, carrots and seasonings to taste) in a slow cooker. Add water and a little olive oil or chicken bones. Add 1 gram of ground cannabis. Cook for 8 hours, topping up the water. Strain the water through a sieve to remove excess cannabis plant matter.

This will infuse your broth with about 100mg of THC. However, these measurements are contingent on what type of cannabis you use and how it is concentrated.

This recipe serves 6. As a result, it should deliver a comfortable buzz. You want to end up with just over 1 litre of broth.


  • About a litre of canna-broth
  • 450 grams of fettuccine
  • 1 small onion
  • 3 cloves of garlic
  • 340 grams of roasted red peppers (usually available in jars)
  • 425 grams of fire roasted diced tomatoes (usually available in cans)
  • 1 tbsp. dried basil
  • ¼ tsp. crushed red pepper
  • Freshly cracked black pepper to taste
  • 113 grams cream cheese (optional)


Add Red Pepper


  • Thinly slice the onion and mince the garlic. Drain the red peppers. Slice them into thin strips.
  • Combine the broth, onion, garlic, red pepper, diced tomatoes, basil and both the red and black pepper. Stir to combine.
  • Break the fettuccine in half. Add it to the pot, submerging pieces as much as possible.
  • Place the lid on the pot and turn the heat to high. When it reaches full boil, give it a quick stir. Be sure to check that pieces of fettuccine do not get stuck on the bottom.
  • Return the lid. Turn the heat down to medium-low for another 10-12 minutes. Once the pasta is tender, remove it from the heat.
  • If you decide to add cream cheese, cut it into tablespoon-sized pieces, then add to the pot. It will melt into a dreamy, creamy sauce.
  • Serve hot.


Each serving should contain about 10mg of THC.


  Guest Writer  

Written by: Guest Writer
Occasionally we have guest writers contribute to our blog here at Zamnesia. They come from a wide range of backgrounds and experiences, making their knowledge invaluable.

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