What Is THCV?
3 min

What Is Thcv?

3 min
Facts News

THCV is a cannabinoid that limits the effects of THC, resulting in a more clear-headed, energetic and euphoric high. It can reduce the negative anxiety inducing effects of THC. THCV also shows great potential in treating a variety of ailments like diabetes and symptoms of Parkinson's disease.

If you are having a hard time keeping up with all the cannabinoids out there, you are not alone. While we are all familiar with the primary cannabinoids and their effects on the human body and mind, there are over a hundred lesser known cannabinoids. One of these lesser known cannabinoids is THCV or Tetrahydrocannabivarin, and it can have quite an impact on your high.

THCV, while not one of the more talked about cannabinoids, holds some very interesting properties. THCV is currently being researched as a primary treatment for a variety of medical ailments, including obesity and diabetes. THCV has only mild psychoactive effect on its own. Much like CBD, the effects can only be felt when activated by the THC present. Despite its potential as a medicinal remedy, if you are looking to get glued to the couch, THCV might actually work against you. THCV has been shown to decrease the intensity of THC and lessen the more unsettling effects of consuming cannabis.




The Chemistry

So, the majority of known cannabinoids are synthesized from a compound called cannabergerol which is found in all cannabis. Cannabergerol undergoes a metabolic process which leads to the creation of THC, CBD and a handful of other cannabinoids. THCV is different. It is not formed from a synthesis of CBG or CBGA. It is formed when divarinolic acid joins with geranyl phosphate. The result is a natural product of the growing process. THCVA or Tetrahydrocannabivaric Acid can then be decarboxylated to create THCV.

When THCV is consumed via smoking cannabis, the molecules fully bind to the CB1 receptors and partially bind to the CB2 receptors. THCV levels are higher than most other cannabinoids, reaching levels of over 50% of total cannabinoids. Although THCV is not listed as a scheduled drug, its chemical structure is close enough to THC that it may be illegal under drug analogue laws.

The Effects

THCV is showing to have some incredible effects on the mind and the body in a clinical setting. On paper, THCV would appear to have some contradictory effects until you take a closer look. Research has shown that THCV restricts the effects of THC, making the experience less intense and reducing the anxiety of those who consumed it. On the other hand, those who have reported on the effects of THCV-rich strains claim that while the experience was of less intensity and caused less anxiety, the high was more euphoric. Having a more euphoric high with less of the stress sounds like a winning combination. One of the downsides of a THCV high is that it only lasts about half as long as a THC high.

THCV is showing incredible promise in the medical field. One study of THCV on mice has shown that it has the ability to alter metabolism and positively affect the symptoms of diabetes. Basically it was found to reduce glucose intolerance and improved insulin sensitivity in the test subjects. It also had the surprising effect of restoring insulin effectiveness in subjects who had previously shown a resistance.

Another promising area of research for THCV includes weight loss and appetite control. THCV has shown to limit the effects of THC in several areas, one of which being the munchies. THCV's effect on your appetite would seem to disprove the stereotype of pizza and chips accompanying your smoke session. Appetite suppression is probably the most exciting characteristic of THCV. Developments in cannabinoid related appetite suppression, combined with THCV's potential to treat diabetes, could make for a life changing therapy for those who need it.

THCV affects the CB1 and CB2 cannabinoid receptors and it has a mild psychoactive effect on its own. The effects of THCV can be described as energetic, clear, focused yet euphoric. It has shown to limit the effects of THC, moderating the high and reducing the anxiety related symptoms some experience from cannabis. It has also shown to have promise in treating the tremors associated with Parkinson's disease. This is due to the neuroprotective effect that THCV has when interacting with the nervous system. Compounds with a neuroprotective effect are used to treat tremors associated with neurological diseases like multiple sclerosis.

Thcv Strains

If you are looking for some THCV-rich strains for their relief properties or just to get a nice relaxing and euphoric high, there are a handful of strains out there that will suit your needs. Durban poison is a world-famous 100% sativa that was born in South Africa and bred in Holland. Durban poison has one of the highest levels of THCV. You will find that THCV-rich strains are typically sativadominant, often having a pure sativa in their lineage. Jack the Ripper is another THCV-rich strain. Its lineage of Cindy 99 brings the genetic of Jack Herer into the mix. The result is one of the highest THCV strains around.

While Durban Poison and Jack the Ripper are two of the more common THCV-rich strains, there are a few other varieties you should know about. Dutch Treat is a popular strain in the clubs throughout Amsterdam. Little is known about its lineage, however, it has shown to be one of the higher THCV cannabis varieties. Also Skunk #1, whose hybrid lineage includes pure Mexican and Colombian sativas, has an overly high THCV content. Skunk #1 is responsible for over 200 skunk varieties that we see today. Any strain that has a lineage stemming from these four is likely to be a high THCV strain.


THCV, while one of the lesser known cannabinoids, has one of the greatest impacts on your high. While only mildly psychoactive by itself, it can offset your high by reducing some of the more anxiety inducing side effects. THCV also interacts with THC in a way that makes for a more euphoric experience. Of all the cannabinoids we know about, THCV shows the most promise in medical applications. It shows a great potential in treating diabetes and weight loss. Its effect on metabolism, insulin signaling and appetite suppression could turn out to be the miracle diet cure we have all wished for. As more and more research on cannabinoids comes in, the more we realize that we have at our fingertips the potential to treat a wide spectrum of ailments. All in all, THCV could turn out to be one of the most beneficial cannabinoids we have discovered yet.


  Guest Writer  

Written by: Guest Writer
Occasionally we have guest writers contribute to our blog here at Zamnesia. They come from a wide range of backgrounds and experiences, making their knowledge invaluable.

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