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Cannabis Research: Epilepsy

Epilepsy is a neurological disorder that causes intense bursts of electrical energy within the brain. It causes a temporary, but recurring disturbance to the way the brain works – resulting in an epileptic seizure. An epileptic seizure can result in loss of consciousness, sensory disturbance and convulsions in addition to many other symptoms.


1) Cannabidiol Displays Antipileptiform and Antiseizure Properties In Vitro and In Vivi (2010)

Research aimed to explore the further implications of CBD for its anticonvulsant properties using both animals and isolated tissue experimentation. It was found that CBD and its effects with CB1 receptors showed the potential to inhibit epileptiform activity within isolated tissue samples, and reduce seizure severity in living animals. Published in the US National Library of Medicine.

2) Cannabidivarin is anticonvulsant in mouse and rats (2012)

Research set out to test the effect of the cannabinoid CBDV on convulsions, such as those caused by epilepsy. It was found that the application of such a cannabinoid was effective at preventing convulsions and appeared to have not side effects on normal functioning. Published in the British Journal of Pharmacology.

3) Marijuana, endocannabinoids, and epilepsy: potential and challenges for improved therapeutic intervention (2013)

This research is a meta-study that outlines how the outcomes of many other studies appear to indicate that cannabinoids, and marijuana, are potentially beneficial to those suffering from neurological disorders, such as epilepsy. Published in the US National Library of Medicine.



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