Diabetes mellitus is a group of diseases that are most commonly associated with defects in insulin production, thus causing blood sugar levels to go unregulated. There are two main types of diabetes, type 1 diabetes and type 2 diabetes. Those suffering with type 1 diabetes are unable to produce their own natural insulin at all and must rely on medication to survive. Those suffering with type 2 diabetes do not produce enough insulin to sustain their bodies. This is a less serious type, and can often be regulated with a strict diet. Leaving diabetes unregulated can lead to kidney failure, blindness, amputations and death.
Diabetes induces nerve pain is one of the most common causes of chronic pain. However, diabetics are thought to be less sensitive to the effects of pain relieving medicines such a morphine and other opiates. This leaves those suffering with few option. This study set out to assess the effectiveness of cannabinoids in helping deal with this pain. Through tests on diabetic mice, they found that cannabinoids potentially have a positive effect on pain reduction. Published in the US National Library of Medicine.
This study set out to find whether the cannabinoid CBD would have any effect on the rate with which the diabetes occurred within type 1 diabetes prone mice. They found that the occurrence of diabetes dropped from a baseline of 86% recorded in an untreated group, to 30% in a group of mice that had received CBD treatment. Published on Ingentaconnect.
This study explores how the non-psychoactive cannabinoid CBD can be applied to reduce damage caused to the retina by diabetes. They found that CBD reduced inflammation, neurotoxicity and blood-retina breakdown in diabetic animals, suggesting that cannabis could be used to prevent diabetic retinopathy. Published in the US National Library of Medicine.