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Cannabis Research: Gastrointestinal Disorders

A Gastrointestinal disorder is a disorder where the bowel looks normal, but does not operate properly. Common examples of such disorder are Irritable Bowel Syndrome (IBS), Inflammatory Bowel Disease (IBD) and constipation.

Related Studies:

1) Cannabinoids and the gastrointestinal tract (2001)

This study aimed to assess the effects of cannabinoids on the gastric system. It was found that the activation of CB1 receptors within the endocannabinoid system inhibited the production of gastric acid, suggesting that it could be used by those who produce too much, and have irritable gastric symptoms. It was also found that there appeared to be no adverse side effects or withdrawals associated with the use of cannabinoids. Published in the journal Gut.

2) Differential Expression of Cannabinoid Receptors in the Human Colon: Cannabinoids Promote Epithelial Wound Healing (2005)

This study sought to seek out the location of cannabinoid receptors within the large intestine and determine their function. It was found that cannabinoid receptors are a common feature within the large intestine and that they may play a role in reducing IBD. Published in the journal Gastroenterology.

3) Endocannabinoids and the gastrointestinal tract (2006)

This research set out to explore the historic use of cannabis remedies to treat gastrointestinal problem, and whether cannabis really does have any effect. It was found that the endocannabinoid system acts to protect the gastric system against abnormalities, having implications into possible treatments available to those who suffer from such conditions. Published in the US National Medical Library of Medicine.

4) Cannabis use amongst patients with inflammatory bowel disease (2011)

Previous research suggests that the endocannabinoid system may play a role in prevent and protecting against inflammation within the large intestines. Through questionnaires assessing the cannabis use habits of those suffering from related disorders, it was found that cannabis use seemed to have a positive therapeutic use, and more research into the matter should be conducted. Published in the US National Library of Medicine.

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